Endocrine Abstracts

Introduction: Inslinomas are the most common cause of hypoglycemia resulting from endogenous hyperinsulinism. Although rare, they have the potential to produce metabolic derangements, necessitating early diagnosis. The aim of our study was to determine the clinical manifestations, diagnostic methods, treatments used and results of patients with insulinoma.Patients and methods: It’s a retrospective study including 9 patients with insulinoma, diagnose...

IntroductionType 1 diabetes (T1D), also known as juvenile diabetes, commonly occurs in young individuals. However, autoimmune diabetes may be diagnosed in the elderly, with different clinical and biological aspects. The aim of our study is to identify the prevalence of and risk factors for microvascular complications related to T1D diagnosed during adulthood.Patients and methodsA retrospective study, from 201...

BackgroundIt’s well known that smoking and diabetes are direct causes for serious health problems such as cancer, and atherosclerosis. It is suggested that smoking indirectly leads to atherosclerosis by influencing nutrient intakes as smokers tend to eat more fat and carbohydrates and less mono unsaturated fats and fiber than non-smokers. But no studies assessed the impact of tobacco on nutrition in diabetic patients.Aim<p...

IntroductionDiabetes mellitus is a serious metabolic disease, described by the World Health Organization as a global epidemic. An alarming increase in its prevalence among adults is observed in Tunisia as everywhere else in the world. Because type 2 diabetes preponderates among adults, few epidemiological studies focused on type 1 diabetes (T1D) that occurs during the adulthood. The aim of this study is to determine the prevalence of DT1 among Tunisian a...

IntroductionMasked arterial hypertension (HTAM) is a relatively recently described entity which gives patients with it the same cardiovascular risk as permanent hypertension. In this context, we report a prospective study including 53 patients in order to determine the prevalence and predictive factors of HTAM in diabetics.MethodsDescriptive prospective study of 53 patients treated in the endocrinology Diabet...

IntroductionType 1 Diabetes (T1D) diagnosed during adulthood is a form of diabetes which is underdiagnosed and underreported. Lower incidence of cardio metabolic risk factors such as atherogenic dyslipidemia, high blood pressure and obesity have been reported in T1D patients compared to type 2 diabetes. In this study, we aimed to determine the prevalence of and predictive factors for macrovascular complications during T1D diagnosed in adulthood.<p cl...

IntroductionPsychogenic polydipsia (PPD), also known as self-induced water intoxication, is mostly seen in psychiatric populations. PPD can lead to life threatening complications and may even be lethal if not diagnosed and treated early. The aim of this study is to determine the clinical and biological features of PPD.Patients and methodsA retrospective study including 11 patients consulting for polydipsia at...

IntroductionThe synthetic anti-oestrogen tamoxifen is the endocrine treatment modality most commonly used for therapy of hormone sensitive breastcancer. The influence of tamoxifen on thyroid function has not been fully elucidated.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular signs. She presented firstly a s...

Introduction: Distal and symmetrical peripheral polyneuropathy is the most frequent type of diabetic neuropathy. Its painful form (PDN) is the most common cause of non-traumatic neuropathic pain and can place a heavy burden on elderly patients’ lives. Despite the major impact that it can have on the quality of life, PDN is generally underdiagnosed because of a large interindividual variability of symptoms and in the absence of well-established diagnostic criteria.<p c...

Introduction: Mitochondrial diabetes (MD) is characterized by a wide spectrum of phenotypic and genotypic manifestations. Through a cohort study of 40 patients with MD, we attempted to establish a correlation between this diversity of phenotypic expression and the biomolecular substrate of the mitochondrial genome within the Tunisian population.Results: Epidemiologically and anthropometrically, our series aligns with literature data, with an onset age of...